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Vitamin D: More may not be better

In recent years, healthy people have been bombarded by stories in the media and on health websites warning about the dangers of too-low vitamin D levels, and urging high doses of supplements to protect...

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Bevacizumab offers first hope for advanced cervical cancer

A new cervical cancer drug offers the first good hope of extending life for women with advanced stages of the disease, according to a study published Sunday.

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Emergency helicopter airlifts help the seriously injured

Patients transferred to hospital via helicopter ambulance tend to have a higher survival rate than those who take the more traditional road route, despite having more severe injuries. The research,...

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New hope in the fight against childhood cancer

Cancer Research UK scientists at the University of Southampton are seeing positive results in a pre-clinical trial that could bring treatments for a particular aggressive form of childhood cancer...

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Treatment beneficial in smoldering multiple myeloma

(HealthDay)—For patients with smoldering multiple myeloma, treatment with lenalidomide plus dexamethasone correlates with delayed progression and improved survival, according to a study published in...

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Molecular marker predicts patients most likely to benefit longest from two...

Johns Hopkins scientists have identified a molecular marker called "Mig 6" that appears to accurately predict longer survival—up to two years—among patients prescribed two of the most widely used drugs...

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Studies confirm shorter radiotherapy course best option for women with breast...

The long-term results of the landmark START trials conclusively confirm that giving radiotherapy as a lower overall dose in fewer, higher doses over a shorter treatment time (hypofractionated) is at...

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Long-term hormonal therapy in intermediate-risk PCa patients does not improve...

A secondary analysis of the historic RTOG 9202 prostate cancer trial examined results of men with intermediate-risk prostate cancer who had received long-term hormonal therapy after radiation therapy,...

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Certain advanced breast cancer patients may benefit from surgery before other...

Patients newly diagnosed with advanced breast cancer and a solitary bone metastasis could benefit from surgery prior to other treatment, according to early results from a first-of-its kind clinical...

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Aspirin use appears linked with improved survival after colon cancer diagnosis

Taking low doses of aspirin (which inhibits platelet function) after a colon cancer diagnosis appears to be associated with better survival if the tumor cells express HLA class I antigen.

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First trial restored under new initiative casts doubt on repeat bowel cancer...

A trial that remained unpublished for 20 years casts doubt on the survival benefit of repeat—'second look'—surgery for bowel cancer.

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Benefit of aggressive prostate CA Tx weakens as comorbidity rises

(HealthDay)—For men with early-stage prostate cancer, the cancer-specific survival benefit associated with aggressive prostate cancer treatment is reduced with increasing comorbidity, according to a...

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ASCO: No benefit for immediate ADT after PSA-only relapse

(HealthDay)—For men with a prostate-specific antigen (PSA)-only-based relapse after prostate surgery or radiation therapy, there seems to be little or no survival benefit for immediate initiation of...

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Research shows overall survival benefit for patients with Stage III soft...

Fox Chase Cancer Center researchers have carried out the first retrospective analysis of adjuvant chemotherapy's impact on overall survival in patients with stage III soft tissue sarcomas (STS),...

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Marginal life expectancy benefit from contralateral prophylactic mastectomy

The choice of contralateral prophylactic mastectomy (CPM) by women with breast cancer (BC) diagnosed in one breast has recently increased in the US but may confer only a marginal life expectancy...

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Breast conserving therapy shows survival benefit compared to mastectomy in...

When factoring in what is now known about breast cancer biology and heterogeneity, breast conserving therapy (BCT) may offer a greater survival benefit over mastectomy to women with early stage,...

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Low sodium levels increases liver transplant survival benefit in the sickest...

Researchers report that low levels of sodium in the blood, known as hyponatremia, increase the risk of dying for patients on the liver transplant waiting list. The study published in Liver...

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Doctors propose tool to help gauge the value of cancer drugs

A doctors group is proposing a formula to help cancer patients decide if a drug is worth it—what it will cost them and how much good it is likely to do.

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Complete resection of high-grade brain cancer yields better survival in...

For children with aggressive brain cancers called high-grade gliomas (HGG), the chances of survival are improved when surgery is successful in eliminating all visible cancer, reports a study in the...

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Removing all visible cancer is key to treating aggressive brain tumors

(HealthDay)—Surgery that removes all visible cancer significantly improves the chances of survival for children with aggressive brain tumors, especially girls.

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Expanding global access to radiotherapy

Queen's University researcher Timothy Hanna has co-authored a Lancet Oncology study that suggests as many as 90 per cent of people in low-income countries lack access to radiotherapy treatment. The...

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CRT may be preferred strategy for elderly with lung cancer

(HealthDay)—Chemoradiotherapy (CRT) is associated with survival benefit over chemotherapy (CT) alone for elderly patients with limited-stage small-cell lung cancer, according to a study published...

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Does radiation therapy improve survival for women with ductal carcinoma in situ?

Approximately 60,000 patients in the United States will receive a diagnosis of ductal carcinoma in situ (DCIS) in 2016. DCIS is not an invasive form of cancer and the 10-year survival rate for women...

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Chemotherapy before chemoradiation shows no survival advantage in head and...

Head and neck cancer patients who receive chemotherapy prior to radiation therapy (induction chemotherapy or IC) rather than the standard treatment that combines chemotherapy with radiation...

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Half of elderly colorectal cancer patients receiving value-less treatment

A study published online ahead of print in the journal Medical Care shows that over a recent 10-year period, the rate of metastatic colorectal cancer patients older than age 75 receiving three or more...

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Rates of prophylactic mastectomy have tripled in past decade despite no...

The use of contralateral prophylactic mastectomy (CPM), the surgical removal of a breast unaffected by cancer as part of the course of treatment for breast cancer, has more than tripled from 2002 to...

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Chemoradiotherapy vs. chemotherapy for locally advanced pancreatic cancer

In a study appearing in the May 3 issue of JAMA, Pascal Hammel, M.D., of Beaujon Hospital, Clichy, France and colleagues assessed whether chemoradiotherapy improves overall survival of patients with...

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Microsurgical head and neck reconstruction is cost-effective

(HealthDay)—For patients with squamous cell carcinoma (SCC), microsurgical head and neck reconstruction is cost-effective compared with locoregional flaps, according to a study published online Nov. 29...

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Critically ill children can still undergo liver transplantation and survive

Advancements in critical care make it possible for even the sickest children to successfully undergo liver transplantation. According to a new study published online as an "article in press" in the...

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Statins may help people with COPD live longer

(HealthDay)—Drugs known as statins may have benefits beyond lowering "bad" LDL cholesterol levels. A new study suggests people with chronic lung disease who take these drugs may extend their survival.

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